Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity

Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity

Summary: Accumulation of visceral adiposity is directly linked to the morbidity of obesity, while subcutaneous body fat is considered more benign. We have identified an unexpected role for B cell lymphoma 6 (BCL6), a critical regulator of immunity, in the developmental expansion of subcutaneous adip...

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Main Authors: Madhavi D. Senagolage, Meredith A. Sommars, Krithika Ramachandran, Christopher R. Futtner, Yasuhiro Omura, Amanda L. Allred, Jianing Wang, Cynthia Yang, Daniele Procissi, Ronald M. Evans, Xianlin Han, Ilya R. Bederman, Grant D. Barish
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718318503

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http://www.sciencedirect.com/science/article/pii/S2211124718318503

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