Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells

<p>Abstract</p> <p>Background</p> <p>In breast cancer, the HER2/<it>neu </it>oncoprotein, which belongs to the epidermal growth factor receptor family, may trigger activation of the phosphoinositide-3 kinase (PI3K)/Akt pathway, which controls cell proliferat...

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Bibliographic Details
Main Authors: Kim Chul-Woo, Jeon Yoon-Kyung, Jang Ji-Young
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/391