Presence of Middle Cerebellar Peduncle Sign in FMR1 Premutation Carriers Without Tremor and Ataxia

Presence of Middle Cerebellar Peduncle Sign in FMR1 Premutation Carriers Without Tremor and Ataxia

Here we report five cases of male FMR1 premutation carriers who present without clinical symptoms of the fragile X-associated tremor/ataxia syndrome (FXTAS), but who on MRI demonstrate white matter hyperintensities in the middle cerebellar peduncles (MCP sign) and other brain regions, a rare finding...

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Bibliographic Details
Main Authors: Jessica L. Famula, Forrest McKenzie, Yingratana A. McLennan, James Grigsby, Flora Tassone, David Hessl, Susan M. Rivera, Veronica Martinez-Cerdeno, Randi J. Hagerman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neurology
Subjects:
FXTAS
MCP sign
movement disorder
MRI
FMR1 premutation
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00695/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00695/full

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