Micromass co-culture of human articular chondrocytes and human bone marrow mesenchymal stem cells to investigate stable neocartilage tissue formation in vitro

Cell therapies for articular cartilage defects rely on expanded chondrocytes. Mesenchymal stem cells (MSC) represent an alternative cell source should their hypertrophic differentiation pathway be prevented. Possible cellular instruction between human articular chondrocytes (HAC) and human bone marr...

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Bibliographic Details
Main Authors: S Giovannini, J Diaz-Romero, T Aigner, P Heini, P Mainil-Varlet, D Nesic
Format: Article
Language:English
Published: AO Research Institute Davos 2010-10-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol020/pdf/v020a20.pdf