Resilience of BST-2/Tetherin structure to single amino acid substitutions

Human tetherin, also known as BST-2 or CD317, is a dimeric, extracellular membrane-bound protein that consists of N and C terminal membrane anchors connected by an extracellular domain. BST-2 is involved in binding enveloped viruses, such as HIV, and inhibiting viral release in addition to a role in...

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Bibliographic Details
Main Authors: Ian R. Roy, Camden K. Sutton, Christopher E. Berndsen
Format: Article
Language:English
Published: PeerJ Inc. 2019-05-01
Series:PeerJ
Subjects:
SNP
Online Access:https://peerj.com/articles/7043.pdf