The Campylobacter jejuni RacRS two-component system activates the glutamate synthesis by directly upregulating γ-glutamyltranspeptidase (GGT)

The highly conserved enzyme γ-glutamyltranspeptidase (GGT) plays an important role in metabolism of glutathione and glutamine. Yet, the regulation of ggt transcription in prokaryotes is poorly understood. In the human pathogen Campylobacter jejuni, GGT is important as it contributes to persistent co...

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Bibliographic Details
Main Authors: Anne-Xander evan der Stel, Andries evan Mourik, Pawel eLanniewski, Jos P.M. van der Putten, Elżbieta K. Jagusztyn-Krynicka, Marc M.S.M. Wosten
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Microbiology
Subjects:
GGT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00567/full