Endogenous PCSK9 may influence circulating CD45neg/CD34bright and CD45neg/CD34bright/CD146neg cells in patients with type 2 diabetes mellitus

Endogenous PCSK9 may influence circulating CD45neg/CD34bright and CD45neg/CD34bright/CD146neg cells in patients with type 2 diabetes mellitus

Abstract Protease proprotein convertase subtilisin/kexin type 9 (PCSK9) is a regulator of LDL cholesterol clearance and has been associated with cardiovascular risk. PCSK9 inhibitors increase in vivo circulating endothelial progenitor cells (EPCs), a subtype of immature cells involved in ongoing end...

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Bibliographic Details
Main Authors: Romina Tripaldi, Paola Lanuti, Paola Giustina Simeone, Rossella Liani, Giuseppina Bologna, Sonia Ciotti, Pasquale Simeone, Augusto Di Castelnuovo, Marco Marchisio, Francesco Cipollone, Francesca Santilli
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88941-x

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https://doi.org/10.1038/s41598-021-88941-x

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