Platelet Lysate Induces in Human Osteoblasts Resumption of Cell Proliferation and Activation of Pathways Relevant for Revascularization and Regeneration of Damaged Bone

Platelet Lysate Induces in Human Osteoblasts Resumption of Cell Proliferation and Activation of Pathways Relevant for Revascularization and Regeneration of Damaged Bone

To understand the regenerative effect of platelet-released molecules in bone repair one should investigate the cascade of events involving the resident osteoblast population during the reconstructive process. Here the in vitro response of human osteoblasts to a platelet lysate (PL) stimulus is repor...

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Bibliographic Details
Main Authors: Van Thi Nguyen, Marta Nardini, Alessandra Ruggiu, Ranieri Cancedda, Fiorella Descalzi, Maddalena Mastrogiacomo
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
platelet lysate (PL)
platelet factors
angiogenesis
osteogenesis
HIF-1α
STAT3
Online Access:https://www.mdpi.com/1422-0067/21/14/5123

Internet

https://www.mdpi.com/1422-0067/21/14/5123

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