<it>IGF2</it>/<it>H19</it> hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome

<it>IGF2</it>/<it>H19</it> hypomethylation is tissue, cell, and CpG site dependent and not correlated with body asymmetry in adolescents with Silver-Russell syndrome

<p>Abstract</p> <p>Background</p> <p>Silver-Russell syndrome (SRS) is characterized by severe intrauterine and postnatal growth failure and frequent body asymmetry. Half of the patients with SRS carry a DNA hypomethylation of the imprinting center region 1 (ICR1) of the...

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Bibliographic Details
Main Authors: Kannenberg Kai, Weber Karin, Binder Cathrin, Urban Christina, Kirschner Hans-Joachim, Binder Gerhard
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Clinical Epigenetics
Subjects:
Silver-Russell syndrome
DNA methylation
Body asymmetry
Skin fibroblast culture
IGF-II
Online Access:http://www.clinicalepigeneticsjournal.com/content/4/1/15

Internet

http://www.clinicalepigeneticsjournal.com/content/4/1/15

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