Regulation of Drug Disposition Gene Expression in Pregnant Mice with Car Receptor Activation

More than half of pregnant women use prescription medications in order to maintain both maternal and fetal health. The constitutive androstane receptor (Car) critically affects the disposition of chemicals by regulating the transcription of genes encoding metabolic enzymes and transporters. However,...

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Bibliographic Details
Main Authors: Amanda S. Bright, Guadalupe Herrera-Garcia, Jamie E. Moscovitz, Dahea You, Grace L. Guo, Lauren M. Aleksunes
Format: Article
Language:English
Published: KenzPub 2016-07-01
Series:Nuclear Receptor Research
Subjects:
Car
Online Access:http://www.kenzpub.com/journals/nurr/2016/101193/