δ-tocotrienol induces human bladder cancer cell growth arrest, apoptosis and chemosensitization through inhibition of STAT3 pathway.

δ-tocotrienol induces human bladder cancer cell growth arrest, apoptosis and chemosensitization through inhibition of STAT3 pathway.

Vitamin E intake has been implicated in reduction of bladder cancer risk. However, the mechanisms remain elusive. Here we reported that δ-tocotrienol (δ-T3), one of vitamin E isomers, possessed the most potent cytotoxic capacity against human bladder cancer cells, compared with other Vitamin E isome...

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Bibliographic Details
Main Authors: Changxiao Ye, Wei Zhao, Minghui Li, Junlong Zhuang, Xiang Yan, Qun Lu, Cunjie Chang, Xiaojing Huang, Ji Zhou, Bingxian Xie, Zhen Zhang, Xin Yao, Jun Yan, Hongqian Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388509?pdf=render

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http://europepmc.org/articles/PMC4388509?pdf=render

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