Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling

Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling

The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change their morphology and position within the cells in response to physiological stimuli and these network rearrangements depend on the microtubule (M...

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Bibliographic Details
Main Authors: Nicola Vajente, Rosa Norante, Nelly Redolfi, Andrea Daga, Paola Pizzo, Diana Pendin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Physiology
Subjects:
spastin
drosophila
microtubules
endoplasmic reticulum
calcium
SOCE
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01544/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01544/full

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