Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

Summary: The process of oligodendrogenesis has been relatively well delineated in the rodent brain. However, it remains unknown whether analogous developmental processes are manifested in the human brain. Here we report oligodendrogenesis in forebrain organoids, generated by using OLIG2-GFP knockin...

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Bibliographic Details
Main Authors: Hyosung Kim, Ranjie Xu, Ragunathan Padmashri, Anna Dunaevsky, Ying Liu, Cheryl F. Dreyfus, Peng Jiang
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111930133X