Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure

Gene-set analysis (GSA) is widely used to infer functional and biological properties of a gene set. Here, the authors develop a conditional and interaction gene-set analysis approach that can considerably refine results from traditional GSA.

Bibliographic Details
Main Authors: Christiaan A. de Leeuw, Sven Stringer, Ilona A. Dekkers, Tom Heskes, Danielle Posthuma
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06022-6