Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a severe progressive muscle disease that is frequently associated with secondary osteoporosis. Previous studies have shown that TGFbeta inactivating antibody improves the muscle phenotype in <i>mdx</i> mice, a model of DMD. In the present study, we as...

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Bibliographic Details
Main Authors: Juliana Marulanda, Iris Boraschi-Diaz, Pierre Beauparlant, Philippe Crine, Frank Rauch
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/8/791