Bispecific T-Cell Redirection versus Chimeric Antigen Receptor (CAR)-T Cells as Approaches to Kill Cancer Cells

The concepts for T-cell redirecting bispecific antibodies (TRBAs) and chimeric antigen receptor (CAR)-T cells are both at least 30 years old but both platforms are just now coming into age. Two TRBAs and two CAR-T cell products have been approved by major regulatory agencies within the last ten year...

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Bibliographic Details
Main Authors: William R. Strohl, Michael Naso
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/8/3/41