Determination of the Dissociation Constants of 16 Active Ingredients in Medicinal Herbs Using a Liquid–Liquid Equilibrium Method

Determination of the Dissociation Constants of 16 Active Ingredients in Medicinal Herbs Using a Liquid–Liquid Equilibrium Method

The dissociation constant is an important physicochemical property of drug molecules that affects the pharmacokinetic and pharmacodynamic properties of drugs. In this study, the distribution coefficients of 16 active ingredients extracted from herbal materials were determined at different pH values...

Full description

Bibliographic Details
Main Authors: Wanying Wang, Baixiu Zheng, Jiahao Wu, Weisong Lv, Peiying Lin, Xingchu Gong
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Separations
Subjects:
liquid–liquid equilibrium method
dissociation constant
distribution coefficient
Caulis Sinomenii
Semen Aesculi
Flos Lonicerae
Online Access:https://www.mdpi.com/2297-8739/8/4/49

Internet

https://www.mdpi.com/2297-8739/8/4/49

Similar Items