Integrin-Rac signalling for mammary epithelial stem cell self-renewal

Abstract Background Stem cells are precursors for all mammary epithelia, including ductal and alveolar epithelia, and myoepithelial cells. In vivo mammary epithelia reside in a tissue context and interact with their milieu via receptors such as integrins. Extracellular matrix receptors coordinate im...

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Bibliographic Details
Main Authors: Safiah Olabi, Ahmet Ucar, Keith Brennan, Charles H. Streuli
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Breast Cancer Research
Subjects:
Wnt
Online Access:http://link.springer.com/article/10.1186/s13058-018-1048-1