New insights emerge as antibody repertoire diversification meets chromosome conformation [version 1; peer review: 3 approved]
Vast repertoires of unique antigen receptors are created in developing lymphocytes. The antigen receptor loci contain many variable (V), diversity (D), and joining (J) gene segments that are arrayed across very large genomic expanses and are joined to form variable-region exons. This process creates...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2019-03-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-347/v1 |