SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)

SOD1 aggregation in astrocytes following ischemia/reperfusion injury: a role of NO-mediated S-nitrosylation of protein disulfide isomerase (PDI)

<p>Abstract</p> <p>Background</p> <p>Ubiquitinated-protein aggregates are implicated in cerebral ischemia/reperfusion injury. The very presence of these ubiquitinated-protein aggregates is abnormal and seems to be disease-related. However, it is not clear what leads to...

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Bibliographic Details
Main Authors: Chen Xueping, Guan Teng, Li Chen, Shang Huifang, Cui Liying, Li Xin-Min, Kong Jiming
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Journal of Neuroinflammation
Subjects:
Nitrosative stress
PDI
S-nitrosylation
SOD1
Ubiquitinated-protein aggregates
Online Access:http://www.jneuroinflammation.com/content/9/1/237

Internet

http://www.jneuroinflammation.com/content/9/1/237

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