Metabolic Landscape of a Genetically Engineered Mouse Model of IDH1 Mutant Glioma

Understanding the metabolic reprogramming of aggressive brain tumors has potential applications for therapeutics as well as imaging biomarkers. However, little is known about the nutrient requirements of isocitrate dehydrogenase 1 (IDH1) mutant gliomas. The IDH1 mutation involves the acquisition of...

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Bibliographic Details
Main Authors: Victor Ruiz-Rodado, Tomohiro Seki, Tyrone Dowdy, Adrian Lita, Meili Zhang, Sue Han, Chunzhang Yang, Murali K. Cherukuri, Mark R. Gilbert, Mioara Larion
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/6/1633