Transfer and Expression of the Interferon Gamma Gene in Human Endothelial Cells Inhibits Vascular Smooth Muscle Cell Growth in Vitro

Intimal hyperplasia in blood vessels is primarily caused by the migration and proliferation of vascular smooth muscle cells. Excessive intimal thickening characterizes atherosclerosis as well as bypass graft and angioplasty failures. Endothelial cell-smooth muscle cell interactions and local cytokin...

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Bibliographic Details
Main Authors: Alison T. Stopeck M.D., Mahmood Vahedian, Stuart K. Williams
Format: Article
Language:English
Published: SAGE Publishing 1997-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979700600103