Pharmacokinetics of BMEDA after Intravenous Administration in Beagle Dogs

The pharmacokinetics of N,N-bis(2-mercapatoethly)-N',N'-diethylenediamine (BMEDA), a molecule that can form a chelate with rhenium-188 (188Re) to produce the 188Re-BMEDA-liposomes, was studied. In this work, beagles received a single injection of BMEDA, at doses of 1, 2, or 5 mg/kg; the co...

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Bibliographic Details
Main Authors: Chih-Hsien Chang, Si-Yen Liu, Te-Wei Lee
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/1/538