Conjugation to the cell-penetrating peptide TAT potentiates the photodynamic effect of carboxytetramethylrhodamine.

Cell-penetrating peptides (CPPs) can transport macromolecular cargos into live cells. However, the cellular delivery efficiency of these reagents is often suboptimal because CPP-cargo conjugates typically remain trapped inside endosomes. Interestingly, irradiation of fluorescently labeled CPPs with...

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Bibliographic Details
Main Authors: Divyamani Srinivasan, Nandhini Muthukrishnan, Gregory A Johnson, Alfredo Erazo-Oliveras, Jongdoo Lim, Eric E Simanek, Jean-Philippe Pellois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3056768?pdf=render