Deep Phenotyping Reveals Distinct Immune Signatures Correlating with Prognostication, Treatment Responses, and MRD Status in Multiple Myeloma

Deep Phenotyping Reveals Distinct Immune Signatures Correlating with Prognostication, Treatment Responses, and MRD Status in Multiple Myeloma

Despite recent advances, Multiple Myeloma (MM) remains an incurable disease with apparent heterogeneity that may explain patients’ variable clinical outcomes. While the phenotypic, (epi)genetic, and molecular characteristics of myeloma cells have been thoroughly examined, there is limited informatio...

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Bibliographic Details
Main Authors: Konstantinos Papadimitriou, Nikolaos Tsakirakis, Panagiotis Malandrakis, Panagiotis Vitsos, Andreas Metousis, Nikolaos Orologas-Stavrou, Ioannis Ntanasis-Stathopoulos, Nikolaos Kanellias, Evangelos Eleutherakis-Papaiakovou, Panagiotis Pothos, Despina Fotiou, Maria Gavriatopoulou, Efstathios Kastritis, Meletios-Athanasios Dimopoulos, Evangelos Terpos, Ourania E. Tsitsilonis, Ioannis V. Kostopoulos
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
multiple myeloma
bone marrow microenvironment
immune profiling
immune signatures
minimal residual disease
Online Access:https://www.mdpi.com/2072-6694/12/11/3245

Internet

https://www.mdpi.com/2072-6694/12/11/3245

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