Anti-cancer effects of 3,5-dimethylaminophenol in A549 lung cancer cells.

Exposure to 3,5-dimethylaminophenol (3,5-DMAP), the metabolite of the 3-5-dimethylaniline, was shown to cause high levels of oxidative stress in different cells. The aim of the present work was to observe whether this metabolite can lead to cytotoxicity, oxidative stress, DNA damage and cell cycle c...

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Bibliographic Details
Main Authors: Pei-Ying Lin, Yu-Jung Chang, Yu-Chen Chen, Chin-Hung Lin, Pinar Erkekoglu, Ming-Wei Chao, Chia-Yi Tseng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6181324?pdf=render