A new rapid kindling variant for induction of cortical epileptogenesis in freely moving rats

A new rapid kindling variant for induction of cortical epileptogenesis in freely moving rats

Kindling, one of the most used models of experimental epilepsy is based on daily electrical stimulation in several brain structures. Unlike the classic or slow kindling protocols (SK), the rapid kindling types (RK) described until now require continuous stimulation at suprathreshold intensities appl...

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Bibliographic Details
Main Authors: Juan Carlos Morales, Carla eAlvarez-Ferradas, Mario eWellmann, Marco eFuenzalida, Manuel eRoncagliolo, Francisco Javier Nualart, Christian eBonansco
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
kindling
Astrogliosis
chronic-epilepsy
cortical-EEG
hippocampal-formation
stereotaxic-surgery
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00200/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00200/full

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