Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

<p>Abstract</p> <p>Background</p> <p>Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood. The aminobisphosphonate alendronate, used to reduce bone loss, has also been shown to inhibit the...

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Bibliographic Details
Main Authors: Väänänen Kalervo, Valta Maija P, Tuomela Johanna M, Härkönen Pirkko L
Format: Article
Language:English
Published: BMC 2008-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/81