Discovering Novel Alternaria solani Succinate Dehydrogenase Inhibitors by in Silico Modeling and Virtual Screening Strategies to Combat Early Blight

Alternaria blight is an important foliage disease caused by Alternaria solani. The enzyme Succinate dehydrogenase (SDH) is a potential drug target because of its role in tricarboxylic acid cycle. Hence targeting Alternaria solani SDH enzyme could be efficient tool to design novel fungicides against...

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Bibliographic Details
Main Authors: Sehrish Iftikhar, Ahmad A. Shahid, Sobia A. Halim, Pieter J. Wolters, Vivianne G. A. A. Vleeshouwers, Ajmal Khan, Ahmed Al-Harrasi, Shahbaz Ahmad
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2017.00100/full