Identification of Critical Molecular Components in a Multiscale Cancer Model Based on the Integration of Monte Carlo, Resampling, and ANOVA

Identification of Critical Molecular Components in a Multiscale Cancer Model Based on the Integration of Monte Carlo, Resampling, and ANOVA

To date, parameters defining biological properties in multiscale disease models are commonly obtained from a variety of sources. It is thus important to examine the influence of parameter perturbations on system behavior, rather than to limit the model to a specific set of parameters. Such sensitivi...

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Bibliographic Details
Main Authors: Zhihui eWang, Veronika eBordas, Thomas eDeisboeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Physiology
Subjects:
sensitivity analysis
Analysis of Variance
agent-based model
Multiscale
Non-small cell lung cancer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00035/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00035/full

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