An Arabidopsis example of association mapping in structured samples.

A potentially serious disadvantage of association mapping is the fact that marker-trait associations may arise from confounding population structure as well as from linkage to causative polymorphisms. Using genome-wide marker data, we have previously demonstrated that the problem can be severe in a...

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Bibliographic Details
Main Authors: Keyan Zhao, María José Aranzana, Sung Kim, Clare Lister, Chikako Shindo, Chunlao Tang, Christopher Toomajian, Honggang Zheng, Caroline Dean, Paul Marjoram, Magnus Nordborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1779303?pdf=render