An Arabidopsis example of association mapping in structured samples.
A potentially serious disadvantage of association mapping is the fact that marker-trait associations may arise from confounding population structure as well as from linkage to causative polymorphisms. Using genome-wide marker data, we have previously demonstrated that the problem can be severe in a...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1779303?pdf=render |