SNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression

SNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression

Abstract Background This investigation was arranged to elucidate whether single nucleotide polymorphisms (SNPs) of lncRNA UCA1 was implicated in elevating colorectal cancer (CRC) risk by interacting with environmental exposures. Methods LncRNASNP database was firstly adopted to predict SNPs that pos...

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Bibliographic Details
Main Authors: Yang Fu, Yizheng Zhang, Jinyuan Cui, Ge Yang, Sanfei Peng, Wunan Mi, Xiangya Yin, Yang Yu, Jianwu Jiang, Qi Liu, Yiyu Qin, Wen Xu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell Communication and Signaling
Subjects:
CRC
lncRNA UCA1
Single nucleotide polymorphism
Gene-environment interaction
miR-873-5p
Nicotine
Online Access:http://link.springer.com/article/10.1186/s12964-020-0518-0

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http://link.springer.com/article/10.1186/s12964-020-0518-0

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