Revealing Functional Crosstalk between Distinct Bioprocesses through Reciprocal Functional Tests of Genetically Interacting Genes

Revealing Functional Crosstalk between Distinct Bioprocesses through Reciprocal Functional Tests of Genetically Interacting Genes

Summary: To systematically explore the genes mediating functional crosstalk between metazoan biological processes, we apply comparative genetic interaction (GI) mapping in Saccharomyces cerevisiae and Caenorhabditis elegans to generate an inter-bioprocess network consisting of 178 C. elegans GIs. Th...

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Bibliographic Details
Main Authors: Dan Chen, Wei Xu, Yu Wang, Yongshen Ye, Yue Wang, Miao Yu, Jinghu Gao, Jielin Wei, Yiming Dong, Honghua Zhang, Xin Fu, Ke Ma, Hui Wang, Zhenrong Yang, Jie Zhou, Wenqing Cheng, Shu Wang, Juan Chen, Barth D. Grant, Chad L. Myers, Anbing Shi, Tian Xia
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313981

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http://www.sciencedirect.com/science/article/pii/S2211124719313981

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