Novel Technology for Protein-Protein Interaction-based Targeted Drug Discovery

We have developed a simple but highly efficient in-cell protein-protein interaction (PPI) discovery system based on the translocation properties of protein kinase C- and its C1a domain in live cells. This system allows the visual detection of trimeric and dimeric protein interactions including cytos...

Full description

Bibliographic Details
Main Authors: Jung Me Hwang, Kyung-Bok Lee, Jong-Soon Choi, Jaerang Rho, Gun-Hwa Kim, Seung Il Kim, Soohyun Kim, Zee-Won Lee
Format: Article
Language:English
Published: SpringerOpen 2011-12-01
Series:Journal of Analytical Science and Technology
Subjects:
Online Access:http://www.jastmag.org/journal/view.php?Type=C&number=58