An Ultra-High Performance Liquid Chromatographic-Tandem Mass Spectrometric Method for the Determination of Sinomenine in Human Plasma after Transdermal Delivery of the Zhengqing Fengtongning Injection

An Ultra-High Performance Liquid Chromatographic-Tandem Mass Spectrometric Method for the Determination of Sinomenine in Human Plasma after Transdermal Delivery of the Zhengqing Fengtongning Injection

A sensitive, precise and selective ultra-high performance liquid chromatography method coupled with triple-quadrupole mass spectrometry was developed and validated for the determination of trace amounts of sinomenine (ng/mL) in minute volumes of human plasma. Fifty microliter plasma samples were p...

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Bibliographic Details
Main Authors: Tingbo Chen, Zheng Xiang, Gengting Dong, Pei Luo, Ping Qiu, Shenzhi Wang, Baoming Huang, Yingyi Wen, Feichi Wu, Liang Liu, Hua Zhou
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Molecules
Subjects:
sinomenine
Zhengqing Fengtongning Injection
transdermal delivery
human plasma
concentration
liquid chromatography-tandem mass spectrometry
Online Access:http://www.mdpi.com/1420-3049/20/4/6454

Internet

http://www.mdpi.com/1420-3049/20/4/6454

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