The Application of Dynamic Models to the Exploration of β1-AR Overactivation as a Cause of Heart Failure

High titer of β1-adrenoreceptor autoantibodies (β1-AA) has been reported to appear in heart failure patients. It induces sustained β1-adrenergic receptor (β1-AR) activation which leads to heart failure (HF), but the mechanism is as yet unclear. In order to investigate the mechanisms causing β1-AR no...

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Bibliographic Details
Main Authors: Xiaoyun Wang, Min Zhao, Xiaoqiang Wang, Shuping Li, Ning Cao, Huirong Liu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2018/1613290