Interaction of Botulinum Toxin with the Epithelial Barrier

Botulinum neurotoxin (BoNT) is a protein toxin (~150 kDa), which possesses a metalloprotease activity. Food-borne botulism is manifested when BoNT is absorbed from the digestive tract to the blood stream and enters the peripheral nerves, where the toxin cleaves core proteins of the neuroexocytosis a...

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Bibliographic Details
Main Author: Yukako Fujinaga
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/974943