E-Cadherin is Critical for SC1-Induced Colony Growth of F9 Embryonic Carcinoma Cells

Background: Colony morphology of embryonic stem (ES) cells contributes to the maintenance of undifferentiated ES cells. Small molecule 3,4-dihydropy-rimido[4,5-d]pyrimidine (SC1), an inhibitor of ERK1- and RasGAP-dependent signaling pathways, can maintain the compact colony morphology of ES cells. H...

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Bibliographic Details
Main Authors: Juan Du, Yongyan Wu, Yingying Liu, Zhiying Ai, Haibo Wu, Xiaoyan Shi, Zekun Guo, Yong Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/358630