A Profound Membrane Reorganization Defines Susceptibility of Plasmodium falciparum Infected Red Blood Cells to Lysis by Granulysin and Perforin

A Profound Membrane Reorganization Defines Susceptibility of Plasmodium falciparum Infected Red Blood Cells to Lysis by Granulysin and Perforin

Malaria remains one of the most serious health problems in developing countries. The causative agent of malaria, Plasmodium spp., have a complex life cycle involving multiple developmental stages as well as different morphological, biochemical and metabolic requirements. We recently found that γδ T...

Full description

Bibliographic Details
Main Authors: Maria Andrea Hernández-Castañeda, Marilyne Lavergne, Pierina Casanova, Bryan Nydegger, Carla Merten, Bibin Yesodha Subramanian, Patricia Matthey, Nils Lannes, Pierre-Yves Mantel, Michael Walch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
blood-stage malaria
pore forming proteins (PFPs)
perforin
granulysin
plasma membrane
cholesterol
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643746/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.643746/full

Similar Items