OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation

OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation

Summary: Oxidation resistance gene 1 (OXR1) protects cells against oxidative stress. We find that male mice with brain-specific isoform A knockout (Oxr1A−/−) develop fatty liver. RNA sequencing of male Oxr1A−/− liver indicates decreased growth hormone (GH) signaling, which is known to affect liver m...

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Bibliographic Details
Main Authors: Mingyi Yang, Xiaolin Lin, Filip Segers, Rajikala Suganthan, Gunn A. Hildrestrand, Johanne E. Rinholm, Per Arne Aas, Mirta M.L. Sousa, Sverre Holm, Nils Bolstad, David Warren, Rolf K. Berge, Rune F. Johansen, Arne Yndestad, Elise Kristiansen, Arne Klungland, Luisa Luna, Lars Eide, Bente Halvorsen, Pål Aukrust, Magnar Bjørås
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472030231X

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http://www.sciencedirect.com/science/article/pii/S221112472030231X

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