Low PCSK-9 levels Are Associated with Favorable Neurologic Function after Resuscitation from out of Hospital Cardiac Arrest

Low PCSK-9 levels Are Associated with Favorable Neurologic Function after Resuscitation from out of Hospital Cardiac Arrest

Endotoxemia after cardiopulmonary resuscitation (CPR) is associated with unfavorable outcome. Proprotein convertase subtilisin/kexin type-9 (PCSK–9) regulates low-density lipoprotein receptors, which mediate the hepatic uptake of endotoxins. We hypothesized that PCSK–9 concentrations are associated...

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Bibliographic Details
Main Authors: Anne Merrelaar, Nina Buchtele, Christoph Schriefl, Christian Clodi, Michael Poppe, Florian Ettl, Harald Herkner, Bernd Jilma, Michael Schwameis, Christian Schoergenhofer
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Journal of Clinical Medicine
Subjects:
inflammation mediators
cardiac arrest
cardiopulmonary resuscitation
critical care outcomes
emergency medicine
lipid metabolism
Online Access:https://www.mdpi.com/2077-0383/9/8/2606

Internet

https://www.mdpi.com/2077-0383/9/8/2606

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