Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1

The antigen-mediated activation of mast cells initiates signaling events leading to their degranulation, to the release of inflammatory mediators, and to the synthesis of cytokines and chemokines. Although rapid and transient microtubule reorganization during activation has been described, the molec...

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Bibliographic Details
Main Authors: Anastasiya Klebanovych, Vladimíra Sládková, Tetyana Sulimenko, Věra Vosecká, Zuzana Rubíková, Martin Čapek, Eduarda Dráberová, Pavel Dráber, Vadym Sulimenko
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
bone marrow-derived mast cells
cell activation
γ-tubulin complexes
microtubule nucleation
SHP-1 tyrosine phosphatase
Online Access:https://www.mdpi.com/2073-4409/8/4/345

Internet

https://www.mdpi.com/2073-4409/8/4/345

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