Necator americanus Ancylostoma Secreted Protein-2 (Na-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site

Necator americanus Ancylostoma Secreted Protein-2 (Na-ASP-2) Binds an Ascaroside (ascr#3) in Its Fatty Acid Binding Site

During their infective stages, hookworms release excretory-secretory (E-S) products, small molecules, and proteins to help evade and suppress the host's immune system. Small molecules found in E-S products of mammalian hookworms include nematode derived metabolites like ascarosides, which are c...

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Bibliographic Details
Main Authors: Ola El Atab, Rabih Darwiche, Nathanyal J. Truax, Roger Schneiter, Kenneth G. Hull, Daniel Romo, Oluwatoyin A. Asojo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Chemistry
Subjects:
venom allergen-like (VAL)
TAPs [testis specific proteins (Tpx)/antigen 5 (Ag5)/pathogenesis related-1 (PR-1)/Sc7]
CAP [cysteine-rich secretory protein (CRISP)/antigen 5/pathogenesis related-1 (PR-1)]
lipid binding
sperm coating protein (SCP)
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2020.608296/full

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https://www.frontiersin.org/articles/10.3389/fchem.2020.608296/full

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