mbImpute: an accurate and robust imputation method for microbiome data

Abstract A critical challenge in microbiome data analysis is the existence of many non-biological zeros, which distort taxon abundance distributions, complicate data analysis, and jeopardize the reliability of scientific discoveries. To address this issue, we propose the first imputation method for...

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Bibliographic Details
Main Authors: Ruochen Jiang, Wei Vivian Li, Jingyi Jessica Li
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-021-02400-4