mbImpute: an accurate and robust imputation method for microbiome data
Abstract A critical challenge in microbiome data analysis is the existence of many non-biological zeros, which distort taxon abundance distributions, complicate data analysis, and jeopardize the reliability of scientific discoveries. To address this issue, we propose the first imputation method for...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-06-01
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Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-021-02400-4 |