Comparison of effects of ivabradine versus carvedilol in murine model with the Coxsackievirus B3-induced viral myocarditis.

BACKGROUND: Elevated heart rate is associated with increased cardiovascular morbidity. The selective I(f) current inhibitor ivabradine reduces heart rate without affecting cardiac contractility, and has been shown to be cardioprotective in the failing heart. Ivabradine also exerts some of its benefi...

Full description

Bibliographic Details
Main Authors: Li Yue-Chun, Zhang Teng, Zhou Na-Dan, Ge Li-Sha, Luo Qin, Guan Xue-Qiang, Lin Jia-Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3386276?pdf=render