RNA Packing Specificity and Folding during Assembly of the Bacteriophage MS2

RNA Packing Specificity and Folding during Assembly of the Bacteriophage MS2

Using a combination of biochemistry, mass spectrometry, NMR spectroscopy and cryo-electron microscopy (cryo-EM), we have been able to show that quasi-equivalent conformer switching in the coat protein (CP) of an RNA bacteriophage (MS2) is controlled by a sequence-specific RNA–protein interaction. Th...

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Bibliographic Details
Main Authors: Ottar Rolfsson, Katerina Toropova, Victoria Morton, Simona Francese, Gabriella Basnak, Gary S. Thompson, Stephen W. Homans, Alison E. Ashcroft, Nicola J. Stonehouse, Neil A. Ranson, Peter G. Stockley
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1080/17486700802168445

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http://dx.doi.org/10.1080/17486700802168445

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