Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells

Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells

Multiple sclerosis (MS) is an inflammatory autoimmune disease characterized by imbalanced immune regulatory networks, and MS patient-derived T effector cells are inefficiently suppressed through regulatory T cells (Treg), a phenomenon known as Treg resistance. In the current study we investigated T...

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Bibliographic Details
Main Authors: Bettina Trinschek, Felix Luessi, Catharina C. Gross, Heinz Wiendl, Helmut Jonuleit
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
therapy
diagnosis
immune regulation
T effector cells
Treg
Online Access:http://www.mdpi.com/1422-0067/16/7/16330

Internet

http://www.mdpi.com/1422-0067/16/7/16330

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