Irinotecan and oxaliplatin: an overview of the novel chemotherapeutic options for the treatment of advanced colorectal cancer

Colorectal cancer is one of the most frequent malignancies in humans and an important cause of cancer death. Metastatic colorectal cancer remains incurable with available systemic therapeutic options. The most active cytotoxic drug against this malignancy, the antimetabolite 5-fluorouracil, was deve...

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Bibliographic Details
Main Authors: I. Grivicich, D.R.A. Mans, G.J. Peters, G. Schwartsmann
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000900001