Reduced chronic restraint stress in mice overexpressing hyperactive proteasomes in the forebrain

Reduced chronic restraint stress in mice overexpressing hyperactive proteasomes in the forebrain

Abstract While chronic restraint stress (CRS) results in depression-like behaviors possibly through oxidative stress in the brain, its molecular etiology and the development of therapeutic strategies remain elusive. Since oxidized proteins can be targeted by the ubiquitin-proteasome system, we inves...

Full description

Bibliographic Details
Main Authors: Ji Hyeon Kim, Ahbin Kim, Yejin Yun, Seoyoung Park, Jung Hoon Lee, Yong-Seok Lee, Min Jae Lee
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Molecular Brain
Subjects:
Proteasome
Gate
Chronic stress
Depression-like behavior
Oxidative stress
Online Access:https://doi.org/10.1186/s13041-020-0548-y

Internet

https://doi.org/10.1186/s13041-020-0548-y

Similar Items