Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection

The progressive loss of immunological memory during aging correlates with a reduced proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that this phenotype is recapitulated during chronic viral infection. The antigenic volume imposed by persistent and latent viruses...

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Bibliographic Details
Main Authors: Marcia Bellon, Christophe Nicot
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Viruses
Subjects:
HIV
EBV
HBV
HCV
HDV
HPV
HSV
VZV
Online Access:https://www.mdpi.com/1999-4915/9/10/289