Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection
The progressive loss of immunological memory during aging correlates with a reduced proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that this phenotype is recapitulated during chronic viral infection. The antigenic volume imposed by persistent and latent viruses...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-10-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/9/10/289 |